Pros

  • Highly effective for extremely dry, cracked, and even bloody knuckles, showing fast relief often noticeable overnight.
  • Works great for hands exposed to harsh conditions, such as frequent washing, cold weather, manual labor, and workouts that create calluses.
  • Creates lonasting hydration by boosting moisture levels and locking it in with a protective layer on the skin.
  • Unscented and hypoallergenic, making it ideal for sensitive skin without irritation.
  • Available in both jar and squeeze tube formats, giving users convenient options with equal effectiveness.
  • A little goes a long way, and it absorbs fairly quickly despite slight initial greasiness.
  • Keeps fingertips and cuticles well moisturized, even with repeated use of antibacterial wipes.
  • Trusted by many as a toated hand cream with quick, transformative hydration.

Cons

  • Initially feels slightly greasy or sticky upon application, requiring careful use of a small amount to avoid ovepplication.
  • Needs to be reapplied frequently after washing hands or using sanitizers to maintain moisture and protection.

Bottom Line

O’Keeffe’s 7 oz Working Hands Hand Cream is a powerhouse solution for anyone battling severely dry or cracked hands, especially in tough environments like winter, manual labor, or constant hand washing. While it starts off a bit greasy, its fast-acting, unscented, and deeply moisturizing formula makes it one of the best healing hand creams out there. If you want quick results that protect and repair, this cream is a top choice — just remember to reapply after washing to keep the magic going. If you prefer a non-greasy feel with similar effectiveness, you might also consider exploring other hand creams designed specifically for sensitive skin, but for sheer restorative power, this one can't be beaten.

Lowest at Amazon
$14.97 at Amazon
Lowest at any Popular Retailer
$13.49 at CVS Pharmacy

Where to Buy

Prices last updated: December 27th 2025 5:47 pm
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