Pros

  • Highly effective at soothing and healing diaper rash quickly, providing fast relief
  • Thick, creamy consistency creates a strong barrier that seals out moisture and protects irritated skin
  • Gentle enough for daily use and suitable for frequent application
  • Clinically proven to protect the skin for up to 12 hours
  • Dermatologis and pediatrician-tested, trusted by medical professionals
  • Free of parabens, phthalates, dyes, and soap, making it hypoallergenic and babafe
  • Recognized as a top choice by parents and childcare providers, with over 20 years of positive reputation
  • Versatile for other skin issues like eczema and heat rash
  • Reliable and effective for multiple children, indicating consistent results
  • Good value for the money considering its multiple benefits

Cons

  • Has a strong, fishy odor that can linger on skin and fabrics
  • Tends to get on surrounding surfaces and fabrics, which may require extra cleanup
  • Some users mention receiving damaged or leaking items, indicating potential packaging issues
  • The smell might be unpleasant for some parents, despite its effectiveness
  • Applying can sometimes be a bit messy due to the thick texture
  • The odor may persist on clothes even after washing, which some find bothersome

Bottom Line

If you're looking for a highly effective, trusted diaper rash cream that offers quick relief and strong protection, Desitin Maximum Strength is a top contender—especially since it’s recommended by pediatricians and loved by parents. Keep in mind the strong odor and potential mess, but for stubborn rashes, this product delivers results. For those sensitive to smells, you might want to consider alternatives, but overall, Desitin remains a reliable go-to for diaper rash relief.

Lowest at any Popular Retailer
$19.48 at Amazon
How we researched this

About this review: We pulled together findings from professional reviews and hundreds of user reviews, and cross-referenced them with ShopSavvy's pricing data from 31 retailers to give you the short version.

Where to Buy

Prices last updated: May 2nd 2026 10:06 pm
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