Best Shirt Stain Removal Methods for 2024

We analyzed top picks from leading reviewers to find the best for every need
Published: April 8th, 2024

👕Dealing with stubborn stains on your favorite shirt? We've all been there. After diving deep into research and conducting hands-on trials, we've found the most effective stain removal methods for 2024.

Whether you're wrestling with greasy spots or the dreaded red wine spill, our top picks have got you covered. Let's check out the best products to help keep your wardrobe looking fresh and clean.

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Overall Best: Method Stain Remover

Method Stain Remover, Free + Clear, 6 Ounce

For the ultimate in stain removal, the Method Stain Remover takes the crown for 2024. This versatile and powerful product effectively handles a broad array of stains, from the ever-dreaded red wine to stubborn olive oil. Its gel formula, paired with a built-in brush, ensures deep penetration for thorough cleaning. Additionally, it’s derived from plant-based ingredients, offering a safer and more eco-friendly option. If you need one reliable stain remover in your arsenal, the Method Stain Remover is your go-to solution.

Lowest at any Popular Retailer
$19.98 at Amazon

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Runner-up: Amodex Ink & Stain Remover

Amodex Products Inc 104 Liquid Ink & Stain Remover 4oz, Fresh and Clean 4 Ounce (Pack of 1)

Our runner-up pick, Amodex Ink & Stain Remover, is a standout for those particularly battling ink stains—even the permanent kind. Its creamy formula works wonders on ink and many other tough stains, although it may fall short on certain food stains like mustard or gravy. Its gentle composition makes it a fantastic choice for delicate fabrics, ensuring that your garments are treated with care while removing those stubborn marks.

Lowest at any Popular Retailer
$11.56 at Amazon

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Budget Pick: Shout Advanced Grease Busting Foam

Shout Advanced Grease Busting Foam, Laundry Stain Remover for Oil and Grease Stains; Works on motor oil, bike grease, cooking oil, and more! 18oz Can

If you're looking for an effective stain remover without breaking the bank, the Shout Advanced Grease Busting Foam is an excellent choice. This budget-friendly option excels at tackling grease and oil stains, making it perfect for food-related mishaps. It's user-friendly and offers great value for money. While it may not be the best on wine stains, its performance on grease ensures your shirts stay spotless without denting your wallet.

Lowest at any Popular Retailer
$3.98 at Amazon

Best for Travel: Tide To Go Instant Stain Remover

Tide to Go Instant Stain Remover 0.34 oz (Pack of 2)

For those who need a quick fix on the go, the Tide To Go Instant Stain Remover is a must-have. This portable, pen-style remover is ideal for fresh stains from grass, chocolate syrup, oil, and more. Its compact size makes it easy to carry in your bag, ensuring you are always prepared for any stain emergencies. Perfect for busy lifestyles, this handy remover keeps your shirts looking their best wherever you are.

Lowest at any Popular Retailer
$14.39 at Amazon

Best for Red Wine Stains: OxiClean Versatile Stain Remover Powder

OxiClean Versatile Stain Remover Powder, 5 lb

Red wine stains can be particularly daunting, but the OxiClean Versatile Stain Remover Powder handles them with ease. Formulated with oxygen-based bleach, this powerful powder can tackle both fresh and set-in stains. While the mixing process might be a bit cumbersome, the results are worth it for one of the toughest stains to remove. Keep this product on hand to rescue your fabrics from those deep red wine splashes.

Lowest at any Popular Retailer
$11.78 at Amazon

Best for Set-In Stains: Grandma’s Secret Spot Remover Laundry Spray

GRANDMA'S Secret GSSR1001 Spot Remover, 2-Ounce, Single Pack, White

When it comes to set-in stains, Grandma’s Secret Spot Remover Laundry Spray is your best bet. It’s highly effective at eliminating older stains that other products struggle with. Though it may have some difficulty with wine and foundation, its overall performance on persistent stains is impressive. Easy to use with a pleasant, light scent, this spray is a great addition to your laundry routine to keep those hard-to-remove spots at bay.

Lowest at any Popular Retailer
$6.50 at Amazon
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