Image 1 of 10
K9 Advantix II for Large Dogs - Image 1
K9 Advantix II for Large Dogs - Image 2
K9 Advantix II for Large Dogs - Image 3
K9 Advantix II for Large Dogs - Image 4
K9 Advantix II for Large Dogs - Image 5
K9 Advantix II for Large Dogs - Image 6
K9 Advantix II for Large Dogs - Image 7
K9 Advantix II for Large Dogs - Image 8
K9 Advantix II for Large Dogs - Image 9
K9 Advantix II for Large Dogs - Image 10
Bayer

K9 Advantix II for Large Dogs

$16.98across 65 retailers
Model: 81520402Color: RedUPC: 724089204028
Lowest at Amazon
$54.00 at Amazon
Price seen Aug 30, 2022
Lowest at any Popular Retailer
$31.98 at 1-800-petmeds
Price seen Jul 25, 2023

Where to Buy

Newest price seen: Sep 20, 2025
RetailerPriceLast seenBuy
P
Petflow
$16.98Jul 25, 2023, may have changedBuy Now
Y
Yow Pet Supplies
$16.98Jul 25, 2023, may have changedBuy Now
W
WalmartPetRx
$17.98Jun 10, 2023, may have changedBuy Now
T
Truegether
Sold by owensonlineventures
$26.69May 22, 2023, may have changedBuy Now
P
PetSupermarket
$29.98Jul 11, 2022, may have changedBuy Now

Prices are collected from retailer listings; each row shows the date we last saw that price. Return and shipping terms are each store's standard policy from our retailer research (April 2026 to May 2026). Some products and categories have different terms, so check with the store before you buy.

Pros

  • •Effective against fleas, ticks, and mosquitoes without requiring pests to bite.
  • •Considered safer than oral medications as it can be washed off if an allergic reaction occurs.
  • •Seen as affordable and positively reviewed by some users.
  • •Can be applied in small amounts over multiple spots on the dog's back for better distribution.

Cons

  • •Can cause adverse reactions such as tingling, redness, itching, and severe allergic responses.
  • •Not safe for cats; it is lethal to them.
  • •Ineffective in preventing tick and flea infestations for several users, despite previous success.
  • •Some dogs experienced discomfort, agitation, and even severe symptoms like seizures and skin irritation.
  • •Noticed a decline in product effectiveness, prompting some users to switch brands.

Bottom Line

While Bayer K9 Advantix II offers broad-spectrum pest protection, it's crucial to monitor dogs for any adverse reactions, especially during the drying period after application. Some users report a decrease in effectiveness against fleas and ticks compared to previous batches. If your dog has a history of allergies or sensitivities, it might be wise to consult a vet before use or consider switching to an alternative product that's proven effective, such as a chewable treatment.

Read full expert review

What Reviewers Are Saying

Criticized
not effective50%
caused allergic reaction40%
disappointed with effectiveness30%
temporary solution20%

Discussion

🔍About This Page

ShopSavvy compares prices across thousands of retailers so you always get the best deal. Prices are collected from retailer listings, and each one shows the date we last saw it. Our expert reviews and community discussion help you make informed buying decisions.

🔥 Trending Deals