Advantage II Large Cat Flea Treatment
Bayer Animal Health

Advantage II Large Cat Flea Treatment

Model: 81520232Color: Blacks & GraysUPC: 724089202321
Lowest at Amazon
$31.38 at Amazon
Price seen Sep 26, 2023
Lowest at any Popular Retailer
$16.98 at chewy
Price seen Jan 30, 2026

Where to Buy

Newest price seen: Jul 19, 2026
RetailerPriceLast seenBuy
chewy logo
chewy
$16.98Jan 30, 2026, may have changedBuy Now
V
Vitacost.com
$17.95Nov 17, 2022, may have changedBuy Now
P
Pets on Broadway
$30.00May 21, 2023, may have changedBuy Now
Amazon logo
Amazon
Sold by Junipers'
$31.38Sep 26, 2023, may have changedBuy Now
walmart logo
walmart
90-day returns (in store too)
$33.59Jan 30, 2026, may have changedBuy Now

Prices are collected from retailer listings; each row shows the date we last saw that price. Return and shipping terms are each store's standard policy from our retailer research (April 2026). Some products and categories have different terms, so check with the store before you buy.

Pros

  • •Effectively reduces flea activity within 12 hours and calms agitated cats within 24 hours.
  • •Does not absorb into the bloodstream; creates a protective barrier on the skin.
  • •Provides peace of mind with noticeable improvement in cat comfort and less itching.
  • •Initial reduction in flea numbers supports continued treatment and monthly regimen for best results.
  • •Appreciated in humid climates, though supplemental treatments might be necessary.
  • •Non-prescription, vet-recommended option offering convenience and flexibility.

Cons

  • •Product's duration may fall short, lasting only 4-5 weeks on indoor cats.
  • •Not ideal for severe infestations; might require additional methods like flea combs or alternative treatments.
  • •Application can be challenging due to fur interference and the need for careful positioning.
  • •Cats may have negative reactions during application; distractions or assistance recommended to ease distress.
  • •Not sufficient as a stand-alone solution; some users experienced continued flea presence prompting a switch to prescription treatments.

Bottom Line

Advantage II Large Cat Flea Treatment is a solid option for indoor cats needing basic flea control, offering an effective start within hours that comforts otherwise agitated pets. However, for cats dealing with stronger infestations or for those who wander in humid and outdoor settings, supplemental strategies or consultation with a vet may yield better, long-term results. Employing the correct application technique and environmental hygiene is crucial for success.

Read full expert review

What Reviewers Are Saying

Praised
happy and relaxed10%
good product for indoor cats10%
Criticized
bald patch from application10%
side effects20%
cat uncomfortable10%
smells strong10%
not as effective10%
flea infestation20%
not worth the risk10%

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Discussion

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