# Differin Acne Treatment Gel *Published: 2025-07-22 | Updated: 2025-07-22 | Source: https://shopsavvy.com/products/differin-acne-treatment-gel* --- **Brand:** Differin **Price Range:** $8.46 - $21.25 across 13 retailers ## Pros - Effectively works on sensitive skin without causing irritation. - Highly effective in clearing skin, with almost immediate results for some users. - Users report clear skin improvement within a week. - Recommended by dermatologists, indicating a level of trust and efficacy. - Gentle on the skin, may not be as strong as prescription options but works similarly to retinol. - Noticeable differences in skin within about 3 days of use. - Considered the best face product by several reviewers. - Highly recommended for others. ## Cons - Users may experience initial redness and purging, where skin may worsen before improving. - Not suitable for use on sensitive areas like the eyes and mouth. - A moisturizer is necessary due to the drying effect. - Some users experienced adverse reactions, especially around under-eye areas. ## About This Product Differin Gel Acne Treatment contains adapalene, an Rx-strength acne-fighting retinoid that helps clear breakouts where they start (works deep into pores in 5 minutes), helps prevents new acne from forming, and as a result, can restore skin's overall tone and texture. Adapalene is the first over-the-counter active ingredient for acne in more than 30 years. It clears acne with the power of an Rx without the prescription, prevents breakouts, blackheads, whiteheads, blemishes and clogged pores, and can be used to effectively treat acne, or maskne, caused by wearing face masks or facial coverings. When used as directed, you could start to see results in as little as 1 week, and when used every single day, Differin Gel can help reduce up to 87% of acne in just 12 weeks (Cunliffe et al 1998, Galderma Laboratories). ## Last Seen Prices | Retailer | Price | Availability | Last seen | Store's standard terms | |----------|-------|-------------|-----------|------------------------| | [Amazon](https://shopsavvy.com/api/redirect/products/HOAdnTCJsi00LkQ5Kb0M/offers/ecnJqJ6Zr4jRbbsxzE8g?source=shopsavvy&medium=product-page) | $8.46 | In Stock | 2023-08-13 (may have changed) | | | [retailers/target](https://shopsavvy.com/api/redirect/products/HOAdnTCJsi00LkQ5Kb0M/offers/zGF8HCog7Isc5K0Lj0Ny?source=shopsavvy&medium=product-page) | $13.49 | In Stock | 2026-01-18 (may have changed) | 90-day returns (in store too) · free return shipping · free shipping on $35+ | | [Walgreens](https://shopsavvy.com/api/redirect/products/HOAdnTCJsi00LkQ5Kb0M/offers/fca233ed-0997-73bf-d251-67563281b52f?source=shopsavvy&medium=product-page) | $14.39 | In Stock | 2024-12-12 (may have changed) | 30-day returns (in store too) | | [Optum Store](https://shopsavvy.com/api/redirect/products/HOAdnTCJsi00LkQ5Kb0M/offers/ef8e547c-2a87-7686-6233-a01058d8898d?source=shopsavvy&medium=product-page) | $14.95 | In Stock | 2024-09-03 (may have changed) | | | [retailers/walmart](https://shopsavvy.com/api/redirect/products/HOAdnTCJsi00LkQ5Kb0M/offers/DwiKqNT7Gy7bnfs7ei2m?source=shopsavvy&medium=product-page) | $14.97 | In Stock | 2025-07-22 (may have changed) | 90-day returns (in store too) | | [Honeybee Health](https://shopsavvy.com/api/redirect/products/HOAdnTCJsi00LkQ5Kb0M/offers/c3d2494e-fc83-02ef-7b6f-96a05dcef834?source=shopsavvy&medium=product-page) | $16.00 | In Stock | 2024-09-03 (may have changed) | | | [CVS (photo)](https://shopsavvy.com/api/redirect/products/HOAdnTCJsi00LkQ5Kb0M/offers/hQMCi4u887Bs1W1B4gr6?source=shopsavvy&medium=product-page) | $17.49 | In Stock | 2022-08-16 (may have changed) | | | [Ulta Beauty](https://shopsavvy.com/api/redirect/products/HOAdnTCJsi00LkQ5Kb0M/offers/OMQGtqcQqoSgt8OEgjoO?source=shopsavvy&medium=product-page) | $17.99 | In Stock | 2022-08-16 (may have changed) | | | [retailers/healthwarehouse](https://shopsavvy.com/api/redirect/products/HOAdnTCJsi00LkQ5Kb0M/offers/qBxeMCnEhl7IBHF1SnrE?source=shopsavvy&medium=product-page) | $19.25 | In Stock | 2025-07-22 (may have changed) | | | [retailers/cvs](https://shopsavvy.com/api/redirect/products/HOAdnTCJsi00LkQ5Kb0M/offers/WtRiCWcWNjC2kLCRuKI2?source=shopsavvy&medium=product-page) | $19.49 | In Stock | 2025-07-22 (may have changed) | | | [retailers/mountainside-medical](https://shopsavvy.com/api/redirect/products/HOAdnTCJsi00LkQ5Kb0M/offers/60bc6014-07c5-bb51-98b2-f76dc0b571c8?source=shopsavvy&medium=product-page) | $21.25 | In Stock | 2025-07-22 (may have changed) | | *Store terms are each retailer's standard return and shipping policy from ShopSavvy's retailer research; some products and categories differ, so check with the store before buying.* [See every retailer and the full price history on ShopSavvy](https://shopsavvy.com/products/differin-acne-treatment-gel) --- *About this page: ShopSavvy compares prices across thousands of retailers, aggregates expert and user reviews, and tracks price history to help you make informed buying decisions. 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